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Table 2 Treatment recommendations

From: Glanders: an overview of infection in humans

Intensive IV therapy Oral eradication therapy
Imipenem 25 mg/kg up to 1 g every six hours TMP-SMX 8/40 mg/kg up to 320 mg/1600 mg every 12 hours
Meropenem 25 mg/kg up to 1 g every eight hours Doxycycline 2.5 mg/kg up to 100 mg every 12 hours
Ceftazidime 50 mg/kg up to 2 g every six hours Amoxicillin-clavulanate 500 mg every eight hours or 875 mg every 12 hours for adults