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Figure 4 | Orphanet Journal of Rare Diseases

Figure 4

From: FGF10 Signaling differences between type I pleuropulmonary blastoma and congenital cystic adenomatoid malformation

Figure 4

Immunohistochemistry with SHH. From left to right, original magnification x 5 (A, C, E, G), x 40 (B, D, F, H). The x 40 magnified area is identified by a rectangle. Counterstain: hematoxilin. A-B: Control lung; Strong expression of SHH in both the epithelium and the underlying mesenchyme of normal bronchi. C-D: CCAM. The expression of SHH is strong and continue within the epithelium lining cysts, and within the mesenchyme. E-G: type I PPB: No SHH staining within the mesenchyme; Focal staining (E-F) or no staining (G-H) in the epithelium lining the cysts.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172