Figure 1

Pedigrees of VP families carrying partial PPOX deletion. Pedigrees of the five families carrying partial PPOX deletion with DNA results and markers for biochemical symptoms. In families A-D affected members carry an exon 5–6 deletion. In family E the patient carries an exon 5–9 deletion. Members in family A-D for whom neither biochemical nor genetic investigation were performed are omitted for simplification.