Figure 1From: A mutation in the serine protease TMPRSS4 in a novel pediatric neurodegenerative disorderOld Order Amish pedigree with consanguinity (indicated by the double lines) has four individuals with ARCA, a disease with an autosomal-recessive mode of inheritance. Affected individuals are shown as blackened squares (male) and circles (female). Diagonal lines across symbols indicate deceased individuals.Back to article page