Table 1 Functional annotation of proteins identified in the novel DNA binding complex
From: A mutation in the c-Fos gene associated with congenital generalized lipodystrophy
Category | Term | EASEScore | Benjamini | Fisher exact | Fold enrichment |
|---|---|---|---|---|---|
GOTERM_MF | Nucleotide binding | 2.20E-07 | 6.80E-06 | 4.10E-08 | 5.3 |
GOTERM_MF | RNA binding | 1.80E-04 | 3.70E-03 | 1.90E-05 | 9 |
GOTERM_MF | Structure-specific DNA binding | 2.10E-04 | 3.30E-03 | 6.90E-06 | 29.8 |
GOTERM_MF | ATP binding | 6.00E-04 | 7.40E-03 | 1.10E-04 | 5.1 |
GOTERM_MF | Adenyl ribonucleotide binding | 6.40E-04 | 6.60E-03 | 1.30E-04 | 5.1 |
GOTERM_MF | Adenyl nucleotide binding | 8.50E-04 | 7.50E-03 | 1.70E-04 | 4.8 |
GOTERM_MF | Ribonucleotide binding | 1.90E-03 | 1.20E-02 | 4.60E-04 | 4.1 |
GOTERM_MF | Purine nucleotide binding | 2.40E-03 | 1.40E-02 | 6.10E-04 | 3.9 |
GOTERM_MF | ATP-dependent helicase activity | 3.00E-03 | 1.50E-02 | 8.70E-05 | 33.1 |
GOTERM_MF | Purine NTP-dependent helicase activity | 3.00E-03 | 1.50E-02 | 8.70E-05 | 33.1 |
GOTERM_MF | Double-stranded telomeric DNA binding | 4.20E-03 | 1.90E-02 | 7.80E-06 | 432.8 |
GOTERM_MF | Protein C-terminus binding | 6.00E-03 | 2.30E-02 | 2.60E-04 | 23 |
GOTERM_MF | Sequence-specific DNA binding | 1.30E-02 | 4.50E-02 | 1.70E-03 | 7.1 |
GOTERM_MF | ATP-dependent DNA helicase activity | 2.10E-02 | 7.00E-02 | 2.30E-04 | 86.6 |
GOTERM_MF | Single-stranded RNA binding | 2.30E-02 | 6.90E-02 | 2.70E-04 | 80.1 |
GOTERM_MF | ATPase activity | 3.10E-02 | 8.90E-02 | 3.10E-03 | 9.7 |
GOTERM_MF | DNA helicase activity | 3.30E-02 | 9.10E-02 | 6.00E-04 | 54.1 |
GOTERM_MF | Single-stranded DNA binding | 4.60E-02 | 1.20E-01 | 1.10E-03 | 39.3 |
GOTERM_MF | DNA-dependent ATPase activity | 4.70E-02 | 1.20E-01 | 1.20E-03 | 38 |
GOTERM_MF | Promoter binding | 4.70E-02 | 1.20E-01 | 1.20E-03 | 38 |
GOTERM_MF | Double-stranded DNA binding | 7.90E-02 | 1.90E-01 | 3.50E-03 | 22.3 |