Skip to main content
Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: A synonymous change, p.Gly16Gly in MECP2 Exon 1, causes a cryptic splice event in a Rett syndrome patient

Figure 1

MeCP2 Domain Structure: NTD: N-terminal domain, MBD: methyl-CpG DNA binding domain, ID: intervening domain, TRD: transcription repression domain and CTD is C-terminal domain. Domain-wise distribution of amino acids of both isoforms of MECP2 protein. Amino acid counts for each domain of MeCP2_E1 was based on that for a previously described MeCP2_E2 domain structure [8].

Back to article page

Orphanet Journal of Rare Diseases

ISSN: 1750-1172