Body fat distribution of patients: magnetic resonance imagery (MRI). (A). T1-weighted MRI axial scans through the arm, forearm, thigh, calf and abdomen of patients 1 and 2, compared with a control woman of similar age (35 yr-old) and BMI (23 kg/m2). Partial lipoatrophy affecting the four limbs, contrasting with accumulation of intra-abdominal fat, was evidenced in both patients. Increased subcutaneous abdominal fat was also striking in patient 1. Bone marrow fat was well preserved. (B). T1-weighted MRI pelvic axial scan in patient 1 and in a control woman (BMI 21 kg/m2), showing lipoatrophy of gluteal fat depots with accumulation of anterior abdominal subcutaneous fat in patient 1.