Figure 1
From: Partial lipodystrophy with severe insulin resistance and adult progeria Werner syndrome

Clinical features of patients. Photographs of patient 1, aged 32 (1, A, B, C, D, E) and patient 2, aged 36 (2, F, G, H, I, J), showing partial lipodystrophy with subcutaneous fat accumulation of the trunk and abdomen with lipoatrophy of the limbs including palms and soles (1, A, B, D, C, E), livedo reticularis of the limbs (B, D, G), sclerodactylia (C, E, I, J), dry, tight and atrophic skin with hyperkeratosis of extremities (B, C, D, E, H, I, J).