Figure 5From: Mutations in the PLEKHG5 gene is relevant with autosomal recessive intermediate Charcot-Marie-Tooth diseaseActivities of wild-type and mutant PLEKHG5. Compared with wild-type, mutant PLEKHG5 proteins have defect in the activation of NF-κB pathway. Luciferase activity measured in HEK293 cells, which were treated with pNF-κB-Luc-reporter and PLEKHG5-expressing vectors. Statistical significance was calculated using Student’s t test: *, p < .05.Back to article page