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Table 1 Cherubism grading system according to Motamedi (1998) and Raposo-Amaral (2007)

From: Cherubism: best clinical practice

Grade I
Lesions of the mandible without signs of root resorption
Class 1 solitary lesion of the mandibular body
  Class 2 multiple lesions of the mandibular body
  Class 3 solitary lesion of the ramus
  Class 4 multiple lesions of the rami
  Class 5 lesions involving the mandibular body and rami
Grade II
Lesions involving the mandible and maxilla without signs of root resorption
Class 1 lesions involving the mandible and maxillary tuberosities
  Class 2 lesions Involving the mandible and anterior maxilla
  Class 3 lesions involving the mandible and entire maxilla
Grade III
Aggressive lesions of the mandible with signs of root resorption
Class 1 solitary lesion of the mandibular body
  Class 2 multiple lesions of the mandibular body
  Class 3 solitary lesion of the ramus
  Class 4 multiple lesions of the mandibular rami
  Class 5 lesions involving the mandibular body and rami
Grade IV
Lesions involving the mandible and maxilla and showing signs of root resorption
Class 1 lesions involving the mandible and maxillary tuberosity
  Class 2 Lesions involving the mandible and anterior maxilla
  Class 3 lesions involving the mandible and entire maxilla
Grade V
The rare, massively growing, aggressive, and extensively deforming juvenile cases involving the maxilla and mandible, and may include the coronoid and condyles
  
Grade VI
The rare, massively growing, aggressive, and extensively deforming juvenile lesions involving the maxilla, mandible and orbits