Figure 4

Glycan analysis by MALDI-TOF MS. Serum transferrin glycan analysis by MALDI-TOF MS in a control (a) and patients 1.1 (b), 2 (c), 3 (d), 4 (e). All the patients showed a defect in sialylation (*). Patients 1.1 (b), 2 (c) and 3 (d) also showed a slight deficient galactosylation (#). Symbols: square: N-acetylglucosamine; white circle: mannose; gray circle: galactose; diamond: sialic acid and triangle: fucose.