Figure 3
From: Clinical and neurocognitive outcome in symptomatic isovaleric acidemia
Clinical signs and laboratory findings at catabolic episodes in symptomatic isovaleric acidemia (IVA). Prevalence of clinical signs and laboratory findings during moderate and severe catabolic episodes (n = 69) of 21 study patients with symptomatic IVA were analyzed as documented in the medical records and/or questionnaires. A) General clinical signs; B) neurological findings; C) clinical chemical and hematologic abnormalities measured in blood and urine at the time of episodes. * Neurologic abnormalities included hyperexcitability, dyscoordination, decreased tendon reflexes.