Table 2 Results of beat pattern: qualitative evaluation and quantitative analysis in non-PCD patients, PCD patients and patients with inconclusive diagnosis
From: Quantitative analysis of ciliary beating in primary ciliary dyskinesia: a pilot study
Patients | Qualitative evaluation | Quantitative analysis | NOn (nl/min) | TEM analysis of cilia | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Abnormal beating (%) | Ciliary dyskinesia score | Weighted distance traveled per sec(μm) | Weighted area swept per sec (μm2) | Abnormal cilia (%) | Main ultrastructural defect | Cilia orientation | |||||
Total | Vi | St | Ci | ||||||||
Group: PCD | |||||||||||
1 | 85 | 55 | 30 | 0 | 2.40 | 1.2 | 3.3 | 15 | 100 | IDA+NL | Poor |
2 | 80 | 70 | 10 | 0 | 2.35 | 0.5 | 1.3 | 0 | 100 | ODA | N |
3 | 95 | 90 | 5 | 0 | 2.83 | 0.0 | 0.0 | 5.9 | 100 | ODA | N |
4 | 50 | 35 | 15 | 0 | 1.45 | 6.2 | 17.5 | 5.7 | 92 | ODA | N |
5 | 55 | 5 | 50 | 0 | 1.4 | 5.8 | 16.0 | 34 | 100 | IDA+NL | N |
6 | 75 | 30 | 45 | 0 | 2.03 | 5.2 | 12.9 | 4.2 | 100 | ODA | N |
7 | 10 | 5 | 5 | 0 | 0.25 | 27.1 | 87.9 | 59.8 | 100 | ODA | N |
8 | 100 | 90 | 10 | 0 | 2.95 | 0.6 | 1.8 | 11.1 | 100 | ODA | N |
9 | 100 | 100 | 0 | 0 | 3 | 0.0 | 0.0 | 6 | 100 | ODA | N |
10 | 100 | 100 | 0 | 0 | 3 | 0.0 | 0.0 | 13 | 100 | ODA | N |
Group: Non-PCD | |||||||||||
11 | 0 | 0 | 0 | 0 | 0 | 53.3 | 184.6 | 809 | 7 | No | N |
12 | 10 | 0 | 10 | 0 | 0.25 | 82.8 | 267.8 | 260 | 1.5 | No | N |
13 | 5 | 0 | 5 | 0 | 0.15 | 53.7 | 148.2 | 219 | 2 | No | N |
14 | 5 | 0 | 5 | 0 | 0.15 | 77 | 256.6 | 194 | 9 | No | N |
15 | 0 | 0 | 0 | 0 | 0 | 76.1 | 236.2 | 661 | 6 | No | N |
16 | 10 | 0 | 10 | 0 | 0.25 | 80.9 | 248.8 | 183 | 2 | No | N |
17 | 20 | 0 | 20 | 0 | 0.5 | 75.6 | 251.5 | 100 | 7 | No | N |
18 | 20 | 0 | 20 | 0 | 0.5 | 34.1 | 95.8 | 639 | 3 | No | N |
19 | 25 | 0 | 25 | 0 | 0.63 | 67.7 | 218.7 | 282 | 2 | No | N |
20 | 25 | 20 | 5 | 0 | 0.73 | 68.1 | 199.8 | 784 | 3 | No | N |
21 | 20 | 0 | 20 | 0 | 0.5 | 39.9 | 116.8 | 264 | 15 | CC | N |
22 | 5 | 0 | 5 | 0 | 0.13 | 50.3 | 163.4 | 132 | 4 | No | N |
23 | 25 | 0 | 25 | 0 | 0.63 | 43.2 | 119.8 | 250 | 0 | No | N |
24 | 0 | 0 | 0 | 0 | 0 | 46.0 | 181.2 | 263 | 3 | No | N |
25 | 5 | 0 | 5 | 0 | 0.13 | 59.6 | 160.8 | 324 | 0 | No | N |
Group: inconclusive diagnosis | |||||||||||
26 | 0 | 0 | 0 | 0 | 0 | 73.3 | 214.8 | 83 | 2 | No | N |
27 | 90 | 80 | 10 | 0 | 2.65 | 0.0 | 0.0 | 17 | 6.5 | Heterogeneous | N |
28 | 60 | 45 | 15 | 0 | 1.75 | 9.1 | 27.3 | 15 | 14 | Heterogeneous | Poor |
29 | 20 | 0 | 20 | 0 | 0.5 | 30.3 | 85.6 | 93 | 21 | ODA | N |
30 | 90 | 90 | 0 | 0 | 2.7 | 0.0 | 0.0 | 5 | 30 | Heterogeneous | N |
31 | 70 | 0 | 70 | 0 | 2.1 | 29.3 | 97.9 | 1 | 0 | No | N |
32 | 55 | 5 | 45 | 5 | 1.40 | 28.6 | 90.1 | 1 | 10 | Heterogeneous | Poor |
33 | 0 | 0 | 0 | 0 | 0.0 | 76.0 | 242.8 | 262 | 55 | ODA+IDA | Poor |
34 | 60 | 15 | 40 | 5 | 1.55 | 5.7 | 17.8 | 6.4 | 22 | CC | N |