Figure 2

Time to the first bone event (BE) in 247 GD patients receiving ERT/SRT. The dashed lines represent the curve’s 95% CI; the estimated probability of BE occurrence after 10 years is reported on the y-axis. (A) Between diagnosis and first treatment during the first 30 years of follow-up. (B) Between first treatment and end of treatment or closing date during 15 years of follow-up. No. at risk represents the number of patients followed at the indicated time; No. with BE represents the number of patients with a BE.