Figure 1From: Leukoencephalopathy with accumulated succinate is indicative of SDHAF1 related complex II deficiency(A-C) Axial T2-weighted and (D) coronal FLAIR-weighted MR images of patient 3 at 9 years of age show widespread bilateral T2-hyperintensities in cerebral periventricular white matter. Involvement of the pons (C, full white arrow) and cystic lesions (D, open arrow) are visible. Peripheral U-fibers are spared. Lesions are largely unchanged compared to neuroimaging at age 4 years1.Back to article page