Targeted massive parallel sequencing: the effective detection of novel causative mutations associated with hearing loss in small families

Table 2 Run statistics and target coverage of NGS in each individual

Family no.	Individual no.	On-target sequenced bases (bp)	Covered target region (bp)	Target coverage (%)	Mean depth (×)	Depth ≥ 10× (%)
KNUF21	III -1	11,555,406	193,337	90.05	54	82.22
KNUF24	II -2	54,927,039	201,347	93.78	256	92.21
	II-5	16,525,672	196,024	91.30	77	85.82
KNUF26	II-3	67,166,957	202,456	94.30	313	92.41
	III-1	9,251,859	192,854	89.83	43	78.26
KNUF29	II-1	12,384,809	195,104	90.87	58	83.71
	III-1	44,392,335	201,109	93.67	207	92.14
KNUF34	II-5	57,045,380	201,906	94.04	263	92.39
	III-3	10,551,804	194,536	90.61	50	82.51
KNUF46	II-2	72,336,591	201,693	93.94	337	92.55
	III-1	14,635,372	195,693	91.15	68	83.51
KNUF57	II-2	51,755,311	200,756	93.51	241	92.20
	III-1	12,911,952	194,467	90.58	60	84.60
KNUF60	I-1	59,181,391	202,284	94.22	276	92.47
	II-3	10,591,967	194,615	90.65	49	82.61

ISSN: 1750-1172