Targeted massive parallel sequencing: the effective detection of novel causative mutations associated with hearing loss in small families

Table 1 Clinical features of patients in 8 Korean families carrying autosomal dominant hearing loss

Family no.	Individual no.	Gender	Age (year)	Mean hearing threshold (dB)		Shape of audiogram	Severity
Family no.	Individual no.	Gender	Age (year)	Left	Right	Shape of audiogram	Severity
KNUF21	III-1^*	Female	1	90	80	-	Severe
KNUF24	II-5	Female	44	39	45	Reverse U-shaped	Moderate
KNUF26	III-1	Female	18	64	65	Sloping	Moderate-severe
KNUF29	II-1	Male	63	54	54	Sloping	Moderate
KNUF34	II-5	Male	66	56	53	Sloping	Moderate
	III-3	Female	21	54	49	Flat	Moderate
KNUF46	II-2	Female	35	99	98	Sloping	Profound
	III-1	Female	9	43	38	Ascending	Mild
	III-2	Male	7	53	53	Ascending	Moderate
	III-3	Male	5	63	68	Ascending	Moderate-severe
KNUF57	III-1	Female	28	84	89	Ski sloping	Severe
	III-2	Male	27	54	45	Flat	Moderate
KNUF60	II-3	Female	33	91	65	Flat	Severe

* The hearing test for III-1 (KNUF21) was performed by auditory brainstem response (ABR).

ISSN: 1750-1172