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Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up and management

Figure 1

MRI of the brain in a case of childhood cerebral ALD showing characteristic extensive white matter changes in the parieto-occipital region and internal capsules on FLAIR sequences (A). This area is initially affected in about 80% of cases of cerebral ALD. The rim enhances after administration of gadolinium on T1 sequences (B). In about 20% of cases the site of initial involvement in cerebral ALD is the frontal white matter as shown on this FLAIR image of a different patient with cerebral ALD (C), with prominent rim enhancement after administration of gadolinium on a T1 weighted image (D).

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