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Table 2 Characteristics of pemphigoid disease-related substrates used in the BIOCHIP mosaic

From: Serological diagnosis of autoimmune bullous skin diseases: Prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy

Disease BP180-NC16A-4X BP230gC
Bullous pemphigoid 42/42 23/42
 Sensitivity 100% 54.8%
 95%CI 91.6-100% 38.7-70.2%
 Specificity 98.2% 100%
 95%CI 96.7-99.3% 98.9-100%
Pemphigus vulgaris 0/65 0/65
Pemphigus foliaceus 0/50 0/50
Linear IgA disease 0/18 0/18
HBD 1/100 0/100
NISD 7/97 0/97
  1. BP230gC, c-terminal globular domain of BP230; HBD, healthy blood donors; NISD, non-inflammatory skin diseases; 95%CI, 95% confidence intervals.