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Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: Serological diagnosis of autoimmune bullous skin diseases: Prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy

Figure 1

BIOCHIP mosaic for immunobullous disorders. (A) On a standard-sized slide, there are ten incubation fields each with six different BIOCHIPs. (B, C) Representative stainings after incubation with a bullous pemphigoid (B) and pemphigus vulgaris (C) serum. Desmoglein (Dsg) 1, Dsg3, and BP230gC (C-terminal globular domain of BP230) are expressed in human HEK293 cells. BP180 NC16A is directly coated on the BIOCHIP. HEK293 cells transfected with pTriEx-1 serve as negative control.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172