Table 1 DMD transcript variants and their tissue expression
Promoters | Publication | Tissue specificity | Alternative splicing | mRNA RefSeq | Protein RefSeq |
|---|---|---|---|---|---|
dp427m | (Koenig et al., 1989)[16] | Skeletal muscle, heart muscle, glial cells | Not referenced | NM_004006.2 | NP_003997.1 |
dp427c | (Chelly et al., 1990)[46] | Brain, retina | Not referenced | NM_000109.3 | NP_000100.2 |
dp427p | (Chelly et al., 1990)[46] | Purkinje cells, muscle | Not referenced | NM_004009.3 | NP_004000.1 |
dp260 | (D'Souza et al., 1995)[47] | Retina | No but two alternative exon 1 | 1: NM_004011.3 | 1: NP_004002.2 |
| Â | Â | Â | Â | 2: NM_004012.3 | 2: NP_004003.1 |
dp140 | (Lidov et al., 1995)[48] | Brain, kidney, retina | No splicing - > dp140 | NM_004013.2 | NP_004004.1 |
|  |  |  | Exons 71 & 78 - > dp140ab | NM_004022.2 | NP_004013.1 |
|  |  |  | Exon 78 - > dp140b | NM_004021.2 | NP_004012.1 |
|  |  |  | Exons 71 to 74 & 78 - > dp140bc | NM_004023.2 | NP_004014.1 |
|  |  |  | Exons 71 to 74 - > dp140c | NM_004020.3 | NP_004011.2 |
dp116 | (Byers et al., 1993)[49] | Schwann cells | Not referenced | NM_004014.2 | NP_004005.1 |
dp71 | (Hugnot et al., 1992)[50] | Everywhere except skeletal muscle | No splicing - > dp71 | NM_004015.2 | NP_004006.1 |
|  |  |  | Exons 71 - > dp71a | NM_004017.2 | NP_004008.1 |
|  |  |  | Exon 71 & 78 - > dp71ab | NM_004018.2 | NP_004009.1 |
|  |  |  | Exon 78 - > dp71b | NM_004016.2 | NP_004007.1 |
|  |  |  | Stop at Exon 70 - > dp40 | NM_004019.2 | NP_004010.1 |