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Table 4 Diagnosis Time Lag (DTL) in the 233 patients, according to Sex, Education Level, Affected Gene, and Index/Non-Index status

From: A long diagnostic delay in patients with Hereditary Haemorrhagic Telangiectasia: a questionnaire-based retrospective study

DIAGNOSIS TIME LAG (DTL)
     Univariate and Multivariate Analysis
     (a) (b) (c)
SEX       
  Total Males Females    
DTL, Mean ± SD (years)
[Range]
25.7 ± 17.4 26.4 ± 19.2 25.1 ± 15.6 p = ns p = ns p = ns
[0;73] [0;73] [0;62]
EDUCATION LEVEL       
  Low Interm High    
DTL, Mean ± SD (years)
[Range]
36.4 ± 18.0 24.5 ± 17.2 21.4 ± 15.2 P < 0.0001 P < 0.05 P < 0.01
[0;73] [0;65] [0;64]
AFFECTED GENE       
  HHT1 HHT2 HHT?    
DTL, Mean ± SD (years)
[Range]
27.7 ± 16.6 23.4 ± 17.3 33.1 ± 19.6 p = ns P < 0.01 p = ns
[0;68] [0;73] [2;61]
INDEX/NON-INDEX STATUS Index Non-Index     
DTL, Mean ± SD (years)
[Range]
29.1 ± 18.0 22.6 ± 16.7   P < 0.01 p = ns P < 0.05
[0;73] [0;68]     
  1. Univariate and multivariate analysis were performed as described in Methods section. (a) Univariate analysis, (b) Multivariate analysis before removal of age, (c) Multivariate analysis after removal of age.