Table 3 First definite diagnosis of HHT in the 233 patients, according to Sex, Education Level, Affected Gene, and Index/Non-Index status

SEX

Total

Males

Females

Age at Diagnosis, Mean ± SD (years)

40.1 ± 17.2

41.2 ± 17.6

38.9 ± 16.8

p = ns

[Range]

[3;78]

[7;78]

[3;73]

EDUCATION LEVEL

Low

Interm

High

Age at Diagnosis, Mean ± SD (years)

53.5 ± 17.4

37.1 ± 16

35.5 ± 14.5

P < 0.0001

[Range]

[3;78]

[4;71]

[7;73]

AFFECTED GENE

HHT1

HHT2

HHT?

Age at Diagnosis, Mean ± SD (years)

37.6 ± 16

39.9 ± 17.5

50.6 ± 17.0

P < 0.02

[Range]

[4;77]

[3;78]

[20;74]

INDEX/NON-INDEX STATUS

Index

Non-Index

Age at Diagnosis, Mean ± SD (years)

45.9 ± 15.3

34.6 ± 17.1

P < 0.001

[Range]

[7;78]

[3;77]