|
SEX
| | | | |
| |
Total
|
Males
|
Females
| |
|
Onset Age, Mean ± SD (years)
|
14.1 ± 11.2
|
14.6 ± 12.6
|
13.6 ± 9.7
|
p = ns
|
|
[Range]
|
[3;60]
|
[3;60]
|
[3;50]
|
|
EDUCATION LEVEL
| | | | |
| |
Low
|
Interm
|
High
| |
|
Onset Age, Mean ± SD (years)
|
17.2 ± 13.4
|
12.2 ± 9.8
|
13.8 ± 10.7
|
p = 0.115
|
|
[Range]
|
[3;51]
|
[3;60]
|
[3;58]
|
|
AFFECTED GENE
| | | | |
| |
HHT1
|
HHT2
|
HHT?
| |
|
Onset Age, Mean ± SD (years)
|
9.9 ± 8.6
|
16.6 ± 12.0
|
17.4 ± 14.4
|
P < 0.0001
|
|
[Range]
|
[3;47]
|
[3;58]
|
[4;60]
|
|
INDEX/NON-INDEX STATUS
| | | | |
| |
Index
|
Non-Index
| | |
|
Onset Age, Mean ± SD (years)
|
16.2 ± 13
|
12.1 ± 9.1
| |
P < 0.02
|
|
[Range]
|
[3;60]
|
[3;49]
| | |
|
CLINICAL ONSET
|
Nr (%)
| | |
|
Epistaxis alone
|
202 (86.7%)
| | |
|
Epistaxis and Mucocut. Tel.
|
15 (6.4%)
| | |
|
Epistaxis and GI bleeding
|
2 (0.9%)
| | |
|
Epist., Mucocut. Tel, and GI bleeding
|
1 (0.5%)
| | |
|
Mucocut Tel. (bleeding + non-bleeding)
|
6 (2.6%)
| | |
|
GI bleeding
|
2 (0.9%)
| | |
|
PAVM-related Accidents
|
2 (0.9%)
| | |
|
CAVM-related Accidents
|
1 (0.5%)
| | |
|
Asymptomatic (only Genetic testing)
|
2 (0.9%)
| | |
