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Table 2 GO Biological processes enriched in lung tissue of ZZ relative to MM COPD

From: Krüppel-like zinc finger proteins in end-stage COPD lungs with and without severe alpha1-antitrypsin deficiency

Term

Gene number (%)

P value

GO:0010033 ~ response to organic substance

19 (14.5%)

<0.0001

GO:0042127 ~ regulation of cell proliferation

20 (15.3%)

<0.0001

GO:0007169 ~ transmembrane receptor protein tyrosine kinase signaling pathway

10 (7.6%)

<0.0001

GO:0009611 ~ response to wounding

15 (11.5%)

<0.0001

GO:0007167 ~ enzyme linked receptor protein signaling pathway

12 (9.2%)

0.0013

GO:0008285 ~ negative regulation of cell proliferation

12 (9.2%)

0.0015

GO:0008283 ~ cell proliferation

13 (9.9%)

0.0019

GO:0050878 ~ regulation of body fluid levels

7 (5.3%)

0.0028

GO:0050817 ~ coagulation

6 (4.6%)

0.0041