Figure 5

Relative mRNA levels for selected genes in lung explants from ZZ AAT deficiency-related emphysema patients treated from 3 to 20 years with AAT augmentation therapy compared to samples from matched, but non-treated patients and MM COPD controls. See Methods for details on microdissection, RNA extraction and RT-PCR. Bars indicate the mean (SE), *p < 0.05 and **p < 0.01.