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Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: Krüppel-like zinc finger proteins in end-stage COPD lungs with and without severe alpha1-antitrypsin deficiency

Figure 1

A: A cluster of functionally related genes, as found by DAVID functional annotation classification, perfectly segregates MM and ZZ COPD samples. This separation is visualized here by multidimensional scaling (MDS). A: Based on the gene expression patterns of the specific functional gene cluster, the pairwise Euclidean distance between the COPD samples is shown in a two-dimensional space. B: The visualization from Figure 1 A is further supported by a heatmap depiction. This heat map shows the relative (z-score) expression level for each gene and sample combination. A high expression level is associated with red, while green represents a low expression level.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172