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Table 3 Determination of mitotic index in cultured lymphocytes from FA patients

From: Improvement of genetic stability in lymphocytes from Fanconi anemia patients through the combined effect of α-lipoic acid and N-acetylcysteine

Mitotic index

Patients

Control group

α-LA 20 μM

NAC 500 μM

α-LA 20 μM + NAC 500 μM

FA8

0,013

0,019

0,023

0,025

FA9

0,029

0,028

0,033

0,037

FA10

0,019

0,019

0,009

0,027

FA11

0,009

0,006

0,013

0,014

FA13

0,011

0,019

0,026

0,036

FA14

0,019

0,018

0,012

0,020

Mean ± SD

0.017 ± 0.007

0.018 ± 0.007

0.019 ± 0.009

0.026 ± 0.009

  1. In control group no antioxidant treatment was done. Abbreviations are explained in Table 1. Paired t-test: Control group vs α-LA 20 μM + NAC 500 μM P < 0.05.
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172