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Figure 2 | Orphanet Journal of Rare Diseases

Figure 2

From: Pulmonary langerhans cell histiocytosis

Figure 2

Light microscopy findings in PLCH. Upper panel shows a low-power microscopic picture with nodular airway-centered lesions showing microcystic change (20×, original magnification, hematoxylin and eosin stain). The lower panel shows diffuse infiltration of lung tissue with Langerhans cells showing vesicular nuclear chromatin, irregular nuclear contour and moderate amount of pale cytoplasm devoid of phagocytosed material. Many eosinophils are also intermixed among Langerhans cells (200× magnification, hematoxylin and eosin stain).

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