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Table 1 GO modules significantly associated to HSCR (FDR-adjusted p--values < 0.01)

From: Four new loci associations discovered by pathway-based and network analyses of the genome-wide variability profile of Hirschsprung’s disease

GO ID

Definition

Significance

(Adj. p-val < 0.05)

GO:0051056

regulation of small GTPase mediated signal transduction

3.216x10-5

GO:0046578

regulation of Ras protein signal transduction

6.825x10-5

GO:0007268

synaptic transmission

4.259 x10-4

GO:0007265

Ras protein signal transduction

8.245 x10-4

GO:0007264

small GTPase mediated signal transduction

3.136 x10-3

GO:0035023

regulation of Rho protein signal transduction

5.369 x10-3

GO:0006816

calcium ion transport

6.978 x10-3

GO:0016337

cell-cell adhesion

0.01203

GO:0006812

cation transport

0.02391

GO:0007167

enzyme linked receptor protein signaling pathway

0.03174

GO:0009966

regulation of signal transduction

0.04825

  1. Values in italics are marginally significant at FDR-adjusted p-values < 0.05.