Skip to main content

Table 1 Age of onset of CMT

From: A locus-specific database for mutations in GDAP1 allows analysis of genotype-phenotype correlations in Charcot-Marie-Tooth diseases type 4A and 2K

  Age of onset Total
  < 10 y 10-30 y > 30 y asymptomatic > 50 y  
Recessive forms 120 (98%) 3 (2%) 0 0 123
Dominant forms 11 (25%) 18 (41%) 9 (20%) 6 (14%) 44
   Domain affected:      
   GST 3 (33%) 2 (22%) 4 (44%) 0 9
   Others 8 (23%) 16 (36%) 5 (14%) 6 (17%) 35
  1. Genotype-phenotype correlation analysis using GDAP1 locus-specific database data evaluating the age of onset according to mode of inheritance and affected domains in dominant forms. Values represent the number of patients for each situation; the corresponding percentages are shown in brackets. y: years; GST: glutathione S-transferase.