Table 6 Analytes that changed significantly during ERT
From: Biomarker analysis of Morquio syndrome: identification of disease state and drug responsive markers
Analyte | Effect of ERT on analyte | p-value |
|---|---|---|
Analytes that increased during ERT | ||
Alpha-1-antitrypsin ഠ| Increase | 0.001 |
Apolipoprotein H | Increase | 0.021 |
Complement 3 ¥ | Increase | 0.000 |
Endothelin-1 ¥ | Increase | 0.000 |
Fibrinogen | Increase | 0.039 |
IgA (immunoglobulin A) | Increase | 0.044 |
IgM (immunoglobulin M) ¥ | Increase | 0.000 |
IGF-1 (insulin-like growth factor 1) | Increase | 0.022 |
Lipoprotein (a) ‡ | Increase | 0.037 |
Serum amyloid P ഠ| Increase | 0.001 |
von Willebrand factor ¥ | Increase | 0.003 |
Analytes that decreased during ERT | ||
CD40 ¥ | Decrease | 0.002 |
Eotaxin ‡ | Decrease | 0.020 |
IL-3 (interleukin-3) ¥ | Decrease | 0.000 |
IL-13 (interleukin-13) | Decrease | 0.015 |