Biomarker analysis of Morquio syndrome: identification of disease state and drug responsive markers

Table 4 Analytes significantly correlated with 6 MWT performances in MPS IVA subjects

Analyte	p-value
Significantly higher in patients with high 6MWT score (> 235) versus lower scores
Apolipoprotein A1	0.011
Apolipoprotein CIII	0.001
Insulin*	0.004
Myoglobin	0.029
Significantly higher in patients with low 6MWT score (< 235) versus higher scores
Adiponectin	0.013
Alpha-2 macroglobulin	0.002
CD40 ligand (cluster of differentiation 40 ligand)	0.034

*This analyte was also significantly different between high and low uKS groups (see Table 5).

ISSN: 1750-1172