From: Biomarker analysis of Morquio syndrome: identification of disease state and drug responsive markers
Analyte | p-value |
---|---|
Significantly higher in older patients (> 9.5 years) versus younger patients | |
IGF-1 (insulin-like growth factor-1) | 0.010 |
IgA (immunoglobulin A)* | 0.002 |
IgM (immunoglobulin M)* | 0.004 |
Significantly higher in younger patients (< 9.5 years) versus older patients | |
Calcitonin | 0.015 |
G-CSF (granulocyte colony-stimulating factor) | 0.044 |
Growth hormone* | 0.003 |
ICAM-1 (intracellular adhesion molecule-1)* | 0.000 |
MMP-2 (matrix metalloproteinase-2)*‡ | 0.019 |
TNF-alpha (tumor necrosis factor alpha)* | 0.000 |
TSH (thyroid stimulating hormone) | 0.023 |
VCAM-1 (vascular cell adhesion molecule-1)* | 0.009 |