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Table 3 Genetic susceptibility factors for AIP and clinical implications.

From: Type 1 autoimmune pancreatitis

Gene Polymorphism/genotype Implication Population
Human leukocyte antigen (HLA) DRB1*0405, DQB1*0401 Increased disease susceptibility Japanese
  Non-aspartic acids at DQβ1 57 Increased relapse risk Korean
Cytotoxic T lymphocyte-antigen (CTLA-4) +49A Increased disease susceptibility Chinese
  +6230G/G Increased disease susceptibility Japanese
  +6230A Decreased disease susceptibility Japanese
  +49A/A, +6230A/A Increased relapse risk Japanese
Tumour necrosis factor-α (TNF-α) -893A Other organ involvement Chinese
Fc receptor-like 3 (FCRL3) -110A/A Increased disease susceptibility Japanese