Table 2 Summary of Simulation Results
From: Benefits, challenges and obstacles of adaptive clinical trial designs
Design | # Patients Expected (N) | # of DLT Expected | Mean MTD (SD) | Prob. of Selecting Correct MTD |
|---|---|---|---|---|
"3+3" TER | 15.96 | 2.8 | 1.26 (0.33) | 0.526 |
"3+3" STER* | 17.56 | 3.2 | 1.02 (0.30) | 0.204 |
CRM(1) | 10.60 | 3.4 | 1.51 (0.08) | 0.984 |
CRM(2) | 13.57 | 2.8 | 1.57 (0.20) | 0.884 |
CRM(3) | 16.37 | 2.7 | 1.63 (0.26) | 0.784 |