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Table 2 Presence of internal neurofibromas in cases and controls

From: At-Risk Phenotype of Neurofibromatose-1 Patients: A Multicentre Case-Control Study

  Cases, n = 106 (%) Controls, n = 102 (%) Odds Ratio* (95%CI) p value**
Paraspinal neurofibromas 54 (51) 20 (20) 4.3 (2.2 - 8.2) < 10 -4
Distribution     
None 52 (49) 82 (81) 1  
Focal 26 (25) 16 (15) 2.6 (1.2 - 5.3)  
Diffuse 28 (26) 4 (4) 14.7 (3.8 - 57.3) < 10-4
Location     
None 52 (49) 82 (81) 1  
Extradural 37 (35) 17 (16) 3.2 (1.6 - 6.4)  
Intradural 17 (16) 3 (3) 8.8 (2.3 - 33.9) < 10-4
Size     
None 52 (49) 82 (81) 1  
< 3 cm 30 (28) 14 (14) 3.4 (1.6 - 7.2)  
≥3 cm 24 (23) 6 (5) 6.3 (2.3 - 17.4) < 10-4
Sciatic neurofibromas 50 (47) 13(13) 6.1 (2.9 - 13.0) < 10 -4
Distribution     
None 63 (60) 90 (88) 1  
Focal 15 (14) 9 (9) 2.7 (1.1 - 6.8)  
Diffuse 28 (26) 3 (3) 15.4 (4.0 - 59.7) < 10-4
Size     
None 56 (53) 89 (88) 1  
< 3 cm 33 (31) 9 (9) 5.8 (2.5 - 13.8)  
≥3 cm 17 (16) 4 (4) 6.8 (2.1 - 22.2) < 10-4
  1. * Odds ratio with 95% confidence interval (95% CI) by logistic regression adjusted for matching variables (age, sex, hospital)
  2. **p value from logistic regression