Table 2 Presence of internal neurofibromas in cases and controls
From: At-Risk Phenotype of Neurofibromatose-1 Patients: A Multicentre Case-Control Study
Cases, n = 106 (%) | Controls, n = 102 (%) | Odds Ratio* (95%CI) | p value** | |
|---|---|---|---|---|
Paraspinal neurofibromas | 54 (51) | 20 (20) | 4.3 (2.2 - 8.2) | < 10 -4 |
Distribution | ||||
None | 52 (49) | 82 (81) | 1 | |
Focal | 26 (25) | 16 (15) | 2.6 (1.2 - 5.3) | |
Diffuse | 28 (26) | 4 (4) | 14.7 (3.8 - 57.3) | < 10-4 |
Location | ||||
None | 52 (49) | 82 (81) | 1 | |
Extradural | 37 (35) | 17 (16) | 3.2 (1.6 - 6.4) | |
Intradural | 17 (16) | 3 (3) | 8.8 (2.3 - 33.9) | < 10-4 |
Size | ||||
None | 52 (49) | 82 (81) | 1 | |
< 3 cm | 30 (28) | 14 (14) | 3.4 (1.6 - 7.2) | |
≥3 cm | 24 (23) | 6 (5) | 6.3 (2.3 - 17.4) | < 10-4 |
Sciatic neurofibromas | 50 (47) | 13(13) | 6.1 (2.9 - 13.0) | < 10 -4 |
Distribution | ||||
None | 63 (60) | 90 (88) | 1 | |
Focal | 15 (14) | 9 (9) | 2.7 (1.1 - 6.8) | |
Diffuse | 28 (26) | 3 (3) | 15.4 (4.0 - 59.7) | < 10-4 |
Size | ||||
None | 56 (53) | 89 (88) | 1 | |
< 3 cm | 33 (31) | 9 (9) | 5.8 (2.5 - 13.8) | |
≥3 cm | 17 (16) | 4 (4) | 6.8 (2.1 - 22.2) | < 10-4 |