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Table 3 Pre-post differences in the behavioural scores of the two groups and change comparison between OT treatment and placebo.

From: Oxytocin may be useful to increase trust in others and decrease disruptive behaviours in patients with Prader-Willi syndrome: a randomised placebo-controlled trial in 24 patients

  Placebo group OT group OT vs. Placebo
Change in behavioural scores Mean SD P-value
(Mann Whitney)
Mean SD P-value
(Mann Whitney)
P-value
(Wilcoxon*)
Isolation tendencies -0.000 0.402 0.723 0.083 0.289 0.317 0.404
Sadness tendencies -0.139 0.324 0.260 0.111 0.533 0.343 0.217
Depressive tendencies -0.097 0.230 0.158 0.056 0.192 0.317 0.088
Self-depreciation -0.056 0.192 0.317 0.056 0.192 0.317 0.166
Self-mutilation 0.042 0.203 0.530 0.194 0.354 0.047 0.236
Conflicts with others 0.083 0.314 0.735 0.208 0.498 0.150 0.532
Disruptive behaviour 0.056 0.457 0.812 0.389 0.385 0.011 0.070
Interest in friendship -0.028 0.497 0.690 0.153 0.379 0.183 0.245
Interest in love affair -0.000 0.632 1.000 -0.069 0.429 0.600 0.704
Trust in others -0.069 0.399 0.850 0.167 0.333 0.084 0.222
  1. * Wilcoxon test is based on individual changes.