Oxytocin may be useful to increase trust in others and decrease disruptive behaviours in patients with Prader-Willi syndrome: a randomised placebo-controlled trial in 24 patients

Table 3 Pre-post differences in the behavioural scores of the two groups and change comparison between OT treatment and placebo.

	Placebo group			OT group			OT vs. Placebo
Change in behavioural scores	Mean	SD	P-value (Mann Whitney)	Mean	SD	P-value (Mann Whitney)	P-value (Wilcoxon*)
Isolation tendencies	-0.000	0.402	0.723	0.083	0.289	0.317	0.404
Sadness tendencies	-0.139	0.324	0.260	0.111	0.533	0.343	0.217
Depressive tendencies	-0.097	0.230	0.158	0.056	0.192	0.317	0.088
Self-depreciation	-0.056	0.192	0.317	0.056	0.192	0.317	0.166
Self-mutilation	0.042	0.203	0.530	0.194	0.354	0.047	0.236
Conflicts with others	0.083	0.314	0.735	0.208	0.498	0.150	0.532
Disruptive behaviour	0.056	0.457	0.812	0.389	0.385	0.011	0.070
Interest in friendship	-0.028	0.497	0.690	0.153	0.379	0.183	0.245
Interest in love affair	-0.000	0.632	1.000	-0.069	0.429	0.600	0.704
Trust in others	-0.069	0.399	0.850	0.167	0.333	0.084	0.222

ISSN: 1750-1172