Figure 1
From: Sensory and motor neuronopathy in a patient with the A382P TDP-43 mutation
Parallel evolution of electroneuromyographic abnormalities (top row) and clinical sensory and motor perturbations (bottom row). The slight neurogenic changes were motor unit potentials (MUPs) with increased polyphasism, size, and duration according to multi-MUP computer-assisted analysis, the active neurogenic changes were fasciculation potentials, fibrillations potentials, or positive sharp waves, while the chronic neurogenic changes were loss of MUPs or high firing rate. 1, abductor policis brevis; 2, first dorsal interosseus; 3, abductor digiti minimi; 4, extensor carpi radialis longus; 5, brachioradialis; 6, palmaris longus; 7, trapezius; 8, vastus lateralis; 9, gastrocnemius; 10, tibialis anterior; 11, extensor digitorum brevis; 12, biceps brachialis; 13, deltoidus; 14, mentalis. The bars correspond to sensory action potentials in μV registered dromically with a surface electrode in the ulnar nerve (head level, normal ≥ 8 μV) and antidromically with the electrode in the sural nerve (foot level, normal ≥ 8 μV).