Table 1 Age-dependent risk for asymptomatic individuals with an MJD a priori risk of 50% (data from Bettencourt et al. [33]).
From: Machado-Joseph Disease: from first descriptions to new perspectives
Age in years | Probability of detectable gene expression | Probability of heterozygous if unaffected |
|---|---|---|
10 | 0.02 | 0.50 |
20 | 0.03 | 0.49 |
30 | 0.22 | 0.44 |
40 | 0.53 | 0.32 |
50 | 0.80 | 0.17 |
60 | 0.96 | 0.04 |
70 | 1.00 | ~0 |