Skip to main content

Table 2 Summary of effects of polyclonal and monoclonal antibodies on parameters measured in this study.

From: Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia

  Glutamate levels Glycerol turnover Cerebello-cortical inhibition Corticomotor response F/M ratio Enzyme inhibition Epitope pattern
Ab SPS Increase No effect No effect No effect Increase Inhibition Inhibition by: b78, b96.11
Ab CA No effect Reduction Decrease Impairment Increase No effect Inhibition by: B78
Ab Ctrl No effect No effect No effect No effect No effect No effect No effect
B96.11 Increase No effect Decrease Impairment Increase No effect Inhibition by: B96.11
B78 Strong increase Reduction Strong decrease Strong impairment Strong increase Inhibition Inhibition by: B78