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Table 1 Review of clinical features associated with IFAP syndrome.

From: Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome

Clinical Feature Percentage of male patients
Congenital alopecia 100
Developmental delay 32
Hypotonia 8
Short stature 25
Microcephaly 17
Frontal bossing 15
Photophobia 100
Dystrophic nails 40
Seizures 28
Intellectual disability 39
Ichthyosis 100
Psoriasiform plaques 32
Cheilitis 24
Lack of sebaceous glands 46
Hypohidrosis 11
Hyperkeratosis 33
Spiny follicular projections 29
Atopic manifestations 36
Recurrent infections 32
Inguinal hernia 18
Vertebral malformations 25
Cleft hand 10