From: Epithelial thymic tumours in paediatric age: a report from the TREP project
N | Tumour type | Age (years) | Stage | Symptoms | Size (cm) | Local extent | Lymph nodes | Metastasis | Surgery | CT | RT (Gy) | Outcome/FU (m) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Thymoma B1 | 4.8 | I | Cough | >5 e <10 | no | no | no | Complete resection at diagnosis | No | No | 1°CR/35.2 |
2 | Thymoma B1 | 12.4 | IVb | Dyspnoea, coma | Kidney, bilaterally | No | No | No | Died | |||
3 | Thymoma B1 | 11.4 | I | Incidental (radiography for scoliosis) | 4×2.5×2 | no | no | no | Complete resection at diagnosis | No | No | 1°CR/93.40 |
4 | Thymoma AB | 15 | I | Chest pain, fever | 16×8×14 | no | no | no | Complete resection at diagnosis | No | No | 1°CR/21.7 |
5 | Lympho-epithelioma-like carcinoma | 11.7 | III | Chest pain, joint pain, fever, butterfly rash, digital clubbing | 12×9×6 | Lung, lymph node | Mediastinal | no | Incomplete resection at diagnosis | Ifo-VCR+ACT (1 cycle) CDDP+VP16 (2 cycles) | 50 | Died/12 |
6 | Carcinoma with neuroendocrine differentiation | 15.5 | IVb | Shoulder pain | 10×6×12 | Sternum, pleural/pericardial effusion | Latero-cervical, mediastinal | Bone | Lymph node biopsy at diagnosis | CDDP+ VP16 (7 cycles) | Yes | Died/17 |
7 | Poorly differentiated carcinoma | 14.7 | IVb | Fever, vomiting, weight loss, abdominal and chest pain | >5 | Lung | Mediastinal | Bone | Lymph node biopsy at diagnosis | CDDP+5FU (1 cycle) CDDP+ADR+VCR+CPM (5 cycles) | 45 | Died/10 |
8 | Poorly differentiated carcinoma | 16.3 | IVb | Cough, fever, fatigue, back pain | >5 e <10 | no | Latero-cervical | Liver, bone | Lymph node biopsy at diagnosis | CDDP+CPM+ADR (4 cycle) | No | Died/7 |
9 | Lympho-epithelioma-like carcinoma | 12 | IVa | Fatigue, weight loss, dyspnoea | 10×10 | Pleural nodes and effusion | Left hylar, mediastinal | no | Incomplete resection after chemotherapy | CDDP+5FU (4 cycles) CDDP (6 cycle) | 54 | Died/16 |