From: Parental risk factors and anorectal malformations: systematic review and meta-analysis
 |  |  | Maternal smoking | Paternal smoking | Smoking of both parents |  | ||
---|---|---|---|---|---|---|---|---|
Ref. |    First author, year | Exposure | OR [95% CI] | P value | OR [95% CI] | P value | OR [95% CI] | Adjustment/matching factors |
[39] |    van Rooij, 2010 | Cigarette consumption before or during pregnancy | 0.8 [0.5, 1.3] | 0.61 | 1.8 [1.1, 2.9]§ | 0.01 | - | - |
[37] |    Miller, 2009§§ | Non-smoker not exposed to ETS Non-smoker exposed to ETS at home or work Non-smoker exposed to ETS at home and work Smoked < 0.5 pack/day Smoked ≥0.5 pack/day Any smoking | 1.0 Reference 1.1 [0.8, 1.5] 1.4 [0.5, 4.0] 1.0 [0.5, 1.8] 1.2 [0.8, 1.7] 1.1 [0.8, 1.6] | - | - |  | - | None of the variables met the criteria for confounding by the author; therefore, only the unadjusted odds ratios were presented |
[31] |    Honein, 2001 | Any smoking 1-5 cigarettes/day 6-10 cigarettes/day 11-20 cigarettes/day ≥21 cigarettes/day | PR: 1.19 [0.94, 1.50] PR: 0.95 [0.60, 1.50] PR: 1.38 [1.00, 1.90] PR: 1.19 [0.80, 1.79] PR: 0.94 [0.29, 2.98] | - | - |  | - | Adjusted for: maternal age, education and race/ethnicity |
[38] |    Stoll, 1997 | Any smoking | 0.98 [0.94, 1.02] | - | - |  | - | - |
[27] |    Cornel, 1996 | Any smoking | 2.24 [1.15, 4.16] | 0.01 | - |  | - | - |
[30] |    Yuan, 1995 | Any smoking | - | - | 1.14 [0.59, 2.18] | 0.70 | 1.75 [0.63, 4.87] | Matched by: maternal age groups (5-years interval), sex, parity and season of birth |
[33] |    Shiono, 1986 | Any smoking | 0.41 [0.09, 1.87] | 0.25 | - |  | - | - |
[42] |    Angerpointer, 1981 | Any smoking ≥5 cigarettes per day | 0.95 [0.45, 1.99]* 0.99 [0.46, 2.14]†1.20 [0.47, 3.10]‡ 0.63 [0.25, 1.57]# 2.30 [1.00, 5.31]* 2.92 [1.16, 7.37]†1.58 [0.51, 4.83]# | 0.89 0.98 0.70 0.32 - | - |  | - | - |