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Table 3 Genetic alterations in Ollier chondrosarcomas

From: Genome-wide analysis of Ollier disease: Is it all in the genes?

Sample

Tumor Grade

Gain

Loss

LOH

Copy neutral LOH

L2218

CS I

-

-

-

-

L204

CS I

1q

3p,4q

3p,4q

-

L253

CS I

1q

6p,6q,9p,12q,13

6p,6q,9p,12q,13

-

L1977

CS I

-

-

-

-

L1685

CS I

-

2q

2q

-

L1687

CS I

3p,7q,8q

-

-

-

L2386

CS I

-

6p,11q

-

-

L2103b

CS I

-

-

-

-

L2221

CS I

14q,17q

-

-

-

L1513

CS I

-

-

-

-

L2280

CS I

-

-

-

-

L2513

CS I

-

-

-

-

L286

CS II

5p,11p,11q,18p

3p,5p,5q,6q,9p,11p,18p,18q

3p,5p,6q,9p,11p,18p,18q

-

L1976

CS II

8q

-

8q

-

L2098

CS II

2,5,7,15,16,17q,18,20,21

10,17q

10,17q

11

L2099

CS II

-

-

-

-

L810

CS III

-

4,5q,6q,9p,12p,13,14q

4,5q,6q,9p,12p,13,14q

-

L2104a

CS III

1q,2p,2q,12p,14q

3q,5q,7q,9p,12p, 22

3q,5q,7q,9p,12p,22

2q

  1. Some of the regions with loss do not show loss of heterozygosity (LOH). This could be explained by the loss of alleles in an aneuploid background.