Table 1 Characteristics of the NF1 patients according to whether their vital status was known or unknown
Clinical features* | KnownVS group n = 1226 No (%)† | UnknownVS group No (%)† | OR (95%CI) ‡ | P value |
|---|---|---|---|---|
Age, years (n = 1893) | 25.9 [2-82]□ | 25.4 [0.2-68]□ | - | 0.19 |
Male gender (n = 1 894) | 579 (47) | 304 (46) | 0.9 (0.8-1.1) | 0.57 |
Familial case (n = 1382) | 515 (57) | 278 (57) | 1.0 (0.8-1.3) | 0.95 |
At least 6 café-au-lait spots (n = 1889) | 1 046 (86) | 584 (87) | 0.9 (0.7-1.2) | 0.56 |
Freckles (n = 1 871) | 1 043 (86) | 509 (78) | 1.7 (1.3-2.2) | <10-4 |
Neurofibromas (n = 1879) | 923 (76) | 495 (75) | 1.0 (0.8-1.3) | 0.87 |
Plexiform neurofibromas (n = 1865) | 361 (30) | 175 (27) | 1.2 (0.9-1.4) | 0.20 |
Lisch nodules (n = 1463) | 382 (40) | 204 (40) | 1.1 (0.8-1.2) | 0.87 |
Renal artery stenosis (n = 1361) | 5 (1) | 3 (1) | 0.7 (0.2-3.1) | 0.70 |
Scoliosis (n = 1373) | 231 (25) | 104 (24) | 1.1 (0.8-1.4) | 0.72 |
Nonunion (n = 1835) | 45 (4) | 20 (3) | 1.2 (0.7-2.0) | 0.57 |
Hydrocephalus (n = 1827) | 32 (3) | 23 (4) | 0.7 (0.4-1.2) | 0.22 |
OBNI (n = 801) | 210 (40) | 105 (38) | 1.0 (0.7-1.4) | 0.96 |
Optic pathway glioma (n = 1812) | 161 (14) | 69 (11) | 1.3 (0.9-1.7) | 0.11 |
MPNSTs (n = 1842) | 80 (7) | 16 (3) | 2.7 (1.6-4.7) | <10-4 |
Pheochromocytoma (n = 1836) | 13 (1) | 7 (1) | 1.3 (0.5-3.7) | 0.61 |