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Table 2 Mean age at death and Standard Deviation (SD) for NF1-associated deaths and all causes (among the general population), by gender, calendar period and age class; Italy, 1995-2006

From: Mortality associated with neurofibromatosis type 1: A study based on Italian death certificates (1995-2006)

ALL AGES

NF1-associated deaths

Mean age at death (SD)

Differences in mean age at death (95% CI)

  

NF1

All causes

NF1 vs. All causes

Total

632

55.5

(21.8)

76.2

(15.2)

20.7

(19.0 - 22.4)

Men

316

53.3

(21.2)

72.8

(15.6)

19.5

(17.2 - 21.9)

Women

316

57.7

(22.1)

79.5

(14.0)

21.8

(19.4 - 24.3)

Gender difference

 

4.4

p ≤ 0.004

6.7

p ≤ 0.0001

  

1995-2000

329

54.4

(22.0)

75.3

(15.5)

20.9

(18.5 - 23.3)

2001-2006

303

56.7

(21.5)

77.0

(14.8)

20.3

(17.9 - 22.7)

Temporal difference

 

2.4

n.s.

1.8

p ≤ 0.0001

  

AGES ≥ 40 years

NF1-associated deaths

Mean age at death (SD)

Differences in mean age at death (95% CI)

  

NF1

All causes

NF1 vs. All causes

Total

447

67.3

(12.9)

77.9

(11.9)

10.6

(9.4 - 11.8)

Men

215

65.5

(12.6)

75.0

(11.8)

9.5

(7.8 - 11.2)

Women

232

68.9

(13.0)

80.7

(11.3)

11.8

(10.1 - 13.5)

Gender difference

 

3.4

p ≤ 0.004

5.7

p ≤ 0.0001

  

1995-2000

230

66.6

(12.9)

77.2

(11.8)

10.7

(9.0 - 12.3)

2001-2006

217

68.0

(12.9)

78.5

(11.9)

10.5

(8.8 - 12.2)

Temporal difference

 

1.4

n.s.

1.3

p ≤ 0.0001

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