A. Preclinical stage | |
---|---|
A1. At-risk stage (50%), one affected parent | - Anxiousness for the future |
 | - Uncertainty about carriership |
 | - Care for affected parent |
A2.Gene carrier, premanifest stage | - Certainty about carriership |
 | - New position in the family |
 | - Renewed uncertainty about onset |
 | - Care for affected parent and own family |
A3. Transition phase | - Strong feelings about changes in cognition |
 | - Changes in behaviour |
 | - Changes in motor activity |
 | - Uncertainty remains |
B. Clinical stage | Â |
B1. Clinical stage I | - Presentation first symptoms: neurological, cognitive or psychiatric |
 | - Chorea most prominent symptom |
 | - Independent in ADL |
 | - Burden for the family mainly psychological |
 | - Rare death, unless suicide |
B2 Clinical stage II | - Motor disturbance more generalised |
 | - Physical dependence starts |
 | - Burden for family psychological and physical |
 | - Death by other cause, suicide, euthanasia |
B3. Clinical stage III | - Severe generalised motor disturbance |
 | - Almost complete physical dependence |
 | - Patient completely dependent on care |
 | - Burden for family mainly physical |
 | - Death |