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Table 3 Summary of studies concerning IVIG for TEN

From: Toxic epidermal necrolysis and Stevens-Johnson syndrome

  Trent Viard Prins Campione Al-Mutairi Shortt Tan Stella Rajaratnam Bachot Brown Schneck
  2003 1998 2003 2003 2004 2004 2005 2007 2010 2003 2004 2008
  (80) (44) (73) (76) (74) (78) (79) (82) (81) (72) (75) (69)
Study design Retro Prosp Retro Prosp Prosp Retro Retro Retro Retro Prosp Retro Retro
  N/ N/ N/ N/ N/ N/ N/ Cont N/ N/ N/ Cont
  Cont Cont Cont Cont Cont Cont Cont   Cont Cont Cont  
Patients 24 10 48 10 12 16 12 23 14 34 24 75
Detachm.(%) 44 39 45 49 58 "65" --- --- "44" 19 49 ---
Total dose IVIG (g/kg) 4 3 3 2 2-5 2.8 2 --- 3.3 2 1.6 1.9 (0.7-2.3)
Predicted mortality (SCORTEN/APACHE*) in % 33 --- --- 35 --- 38 * --- 35.8 36 24 28.6 25
Actual mortality in % 4 0 12 10 0 25 8 26 21 32 41.7 34