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Figure 2 | Orphanet Journal of Rare Diseases

Figure 2

From: Prediction of the responsiveness to pharmacological chaperones: lysosomal human alpha-galactosidase, a case of study

Figure 2

Responsiveness to DGJ and solvent accessibility. Occurrences of responsive or non responsive mutations in accessible (blue bars) or non accessible (red bars) residues are reported as percentage: we used a cut-off of 5.0% as a threshold of side-chain solvent accessibility. Differences between percentage shown in blue and red bars are statistically significant (p = 0.03).

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